Natural
Viagra? Horny Goat Weed Shows Promise In 2008
Lab
Study
Medical
News Today, September 25, 2008. Move over, Viagra!
Researchers in Italy
report that an ancient Chinese herbal remedy known as "horny goat
weed" shows
potential in lab studies as source for new future drugs to treat
erectile dysfunction (ED).
The study, which provides scientific evidence supporting
the herb's well-known use as a
natural aphrodisiac, is scheduled for the
October 24, 2008, issue of ACS' Journal of
Natural Products, a monthly
publication, in the article "Potent Inhibition of Human
Phosphodiesterase-5 by Icariin Derivatives"
In the new study, Mario Dell'Agli and colleagues point out that Viagra
(sildenafil) and
several other prescription drugs are now available for ED, or male
impotence. ED
affects an estimated 18 million men in the United States alone. Studies
show, however,
that these drugs may cause side effects such as headache, facial
flushing, stomach upset,
and visual disturbances.
To find better treatments, the scientists studied herbal extracts reputed
to improve sexual
performance. Scientists exposed the substances to an enzyme that
controls blood flow
to the penis and whose inhibition results in an erection. Of
the extracts tested, "horny
goat weed" was the most potent inhibitor of the enzyme. By chemical modification of
icariin, the active ingredient purified from the
extract, the scientists obtained a derivative
with activity similar to Viagra and a
potential for fewer side effects because it targeted
the protein more precisely than sildenafil.- MTS
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